For clozapine safety, which concerns should be monitored per protocol?

• A. Signs of infection and myocarditis
• B. Metabolic panel only
• C. Blood pressure only
• D. None

Answer: (A)

Clozapine safety hinges on watching for infection risk and heart-related inflammation, especially early after starting the medication. Neutropenia can raise the chance of serious infections, so prompt attention to infection signs—like fever, malaise, or sore throat—guides timely ANC checks and intervention. At the same time, myocarditis is a known risk during the first weeks of treatment, so monitoring for symptoms such as chest pain, shortness of breath, palpitations, or unusual fatigue helps detect this condition early and adjust therapy as needed. While metabolic health and blood pressure are important for overall care, the protocol-focused safety concerns emphasized here are infection signs and myocarditis. That alignment makes this option the best fit.